What is Altitude Sickness?

Altitude sickness, also known as acute mountain sickness (AMS), occurs when you ascend to high altitudes too quickly, typically above 2,500 meters (8,200 feet). The reduced oxygen levels at high elevations can cause symptoms such as headache, nausea, fatigue, dizziness, and shortness of breath.

Who Should Consider Acetazolamide?

Acetazolamide is commonly used to prevent and reduce the symptoms of altitude sickness. It is recommended for:

Travelers ascending quickly to high elevations (e.g., trekking in the Andes, Himalayas, Alps, or Rockies)
Mountaineers and hikers planning climbs over 2,500 meters
Skiers and snowboarders visiting high-altitude resorts
Pilgrims or tourists heading to high-altitude regions without time for gradual acclimatization
Individuals with a prior history of altitude sickness

What is the Typical Acetazolamide Dosage for Altitude Sickness?

The typical preventive dosage is:

125–250 mg twice daily, starting 1–2 days before ascent
Continue taking it for 2–3 days after reaching your highest altitude, or longer if symptoms persist

Your healthcare provider will advise you on the most appropriate dose based on your medical history and travel plans.

Can Acetazolamide Be Used After Symptoms Start?

Yes. Acetazolamide can also be used after symptoms of altitude sickness begin, to speed up recovery in conjunction with rest or descent. However, prevention is usually more effective than treatment after symptoms have started.

What are the Side Effects of Acetazolamide?

Acetazolamide is generally well tolerated, but possible side effects include:

Tingling or numbness in fingers, toes, or lips
Increased urination
Taste alterations (especially for carbonated drinks)
Drowsiness or fatigue
Rare allergic reactions (seek medical help if this occurs)

Are There Any Restrictions or Considerations?

Not suitable for individuals allergic to sulfa drugs
Caution in people with kidney, liver, or adrenal gland problems
Avoid during pregnancy
Hydration is important while taking acetazolamide

Is Acetazolamide Safe for Children?

Yes, acetazolamide can be used in children over the age of 12 for altitude sickness prevention, but dosing must be determined by a healthcare provider.

What is the Cost per Course?

The cost for a full preventive course of acetazolamide (typically 10–14 tablets) at our pharmacy is £29.